Itraconazole, Quantitative by LC-MS/MS ITRACO

Method(s) Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry
Specimen Required
Collect

One 5 mL plain red top tube. Alxo acceptable: lavender (EDTA) or green (sodium or lithium heparin) top tubes.

Transport 1 mL serum frozen. (Min: 0.6 mL)
Remarks

Timing of specimen collection: Pre-dose (trough) draw - at steady state concentration.

Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 48 hours; Frozen: 6 months

Unacceptable Conditions Serum separator tubes. Hemolyzed or lipemic specimens.
Schedule Tue, Thu, Sat
Billing Code 5011295
CPTCode 80299
Preferred Specimen Collection Device(s)
Reference Interval
 
 Therapeutic Ranges
Itraconazole (trough) - Localized Infection
Greater than 0.5 µg/mL
Itraconazole (trough) - Systemic InfectionGreater than 1.0 µg/mL
HydroxyitraconazoleNo therapeutic range established

Total concentrations for itraconazole and hydroxyitraconazole should not exceed 10 µg/mL.

No Appointment Necessary
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12 Patient Service Centers in Central New York.

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