Valproic Acid, Free & Total VPA

Method(s) Immunoassay
Specimen Required
Collect One 6 mL plain red top tube. Separate serum from cells within 2 hours of collection.
Transport 2 mL serum at 2-8°C. (Min: 1 mL)
Stability

After separation from cells: Ambient: 24 hours; Refrigerated: 1 week; Frozen: 1 month

Unacceptable Conditions Plasma. Tubes that contain liquid anticoagulant. Serum Separator Tubes (SST).
Schedule Tue-Sat
Billing Code 5011570
CPTCode 80164; 80165
Notes Separate serum from cells within 2 hours of collection. Do not use heparin as an anticoagulant.
Preferred Specimen Collection Device(s)
Reference Interval
 
Available SeparatelyComponentReference Interval
NoValproic Acid, TotalTherapeutic Range: 50-125 ug/mL
  Toxic: Greater than 150 ug/mL

No

Valproic Acid, Free

Effective: November 18, 2013

  Therapeutic Range: 7-23 ug/mL
  Toxic: Greater than 30 ug/mL

No

VPA-percent Free

5-18%

No Appointment Necessary
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12 Patient Service Centers in Central New York.

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