Maternal Serum Screen, Alpha Fetoprotein, hCG, Estriol, and Inhibin A (Quad) MSSQ
|Method(s)||Quantitative Chemiluminescent Immunoassay|
One 5 mL gold (SST) or plain red top tube.
Separate serum from cells ASAP or within 2 hours of collection. Transfer 3 mL serum refrigerated to an ARUP Standard Transport Tube. (Min: 1 mL)
Submit with Order: Patient's date of birth, current weight, due date, dating method (US, LMP), number of fetuses present, patient's race, if the patient was diabetic at the time of conception, if there is a known family history of neural tube defects, if the patient has had a previous pregnancy with a trisomy, if the patient is currently smoking, if the patient is taking valproic acid or carbamazepine (Tegretol), if this is a repeat sample, and the age of the egg donor if in vitro fertilization.
Collection to initiation of testing: After separation from cells: Ambient: 72 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles).
Plasma. Hemolyzed specimens.
|Notes||See attached required requisition and patient consent. Patient Prep: Specimen must be drawn between 14 weeks, 0 days and 24 weeks, 6 days gestation. The recommended time for maternal serum screening is 16 to 18 weeks gestation.|
|Preferred Specimen Collection Device(s)|