Carbamazepine Epoxide & Total CARBAM

Method(s) Quantitative Liquid Chromatography-Tandem Mass Spectrometry/Quantitative Enzyme Multiplied Immunoassay Technique
Specimen Required
Collect One 5 mL plan red top tube, or lavender (EDTA), or pink (K2EDTA) top tube.
Transport 1 mL serum at 2-8°C. (Min. 0.5 mL)
Remarks Patient Prep: Obtain trough specimen after steady-state is achieved (3-5 days). Draw within one hour prior to next dose. The epoxide half-life is 6-10 hours.
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 6 days; Frozen: 1 month.

Unacceptable Conditions

Whole blood, separate tubes, light blue (citrate) or yellow (SPS or ACD solution) top tubes.

Schedule Mon, Thu
Billing Code 5011422
CPTCode 80156, 80299
Notes Separate serum or plasma from cells within 2 hours of collection.
Preferred Specimen Collection Device(s)
Reference Interval

Carbamazepine -10, 11 Epoxide: Not well established
Toxic: Greater than 15.0 ug/mL

Total Carbamazepine: Therapeutic Range: 4.0-12.0 µg/mL
Toxic: Greater than 20.0 µg/mL

 

No Appointment Necessary
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12 Patient Service Centers in Central New York.

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