F-Actin Antibody, IgG with Reflex to Smooth Muscle Antibody, IgG Titer ACTIGG

Method(s) Enzyme Linked Immunosorbent, Indirect Fluorescent Antibody
Synonym Smooth Muscle Antibody
Specimen Required
Collect

One 5 mL gold (SST) top tube.

Transport 1 mL serum at 2-8°C. (Min: 0.5 mL)
Stability

Ambient: 8 hours; Refrigerated: 7 days

Unacceptable Conditions Plasma, lipemic, contaminated, hemolyzed, or heat-activated specimens.
Schedule Mon, Thurs
Billing Code 2010220
CPTCode 83516 Actin IgG; if reflexed, add 86256 ASMR Titer
Notes If F-Actin is 20 units or greater, Smooth Muscle Antibody, IgG IFA titer will be added.
Preferred Specimen Collection Device(s)
Reference Interval
ComponentsReference Interval
F-Actin (Smooth Muscle) Antibody, IgG

Negative: less than 20 Units.

Weak Positive: 20-30 Units.

Moderate to Strong Positive: greater than 30 Units.

Smooth Muscle Antibody, IgG Titer

Less than 1:20 = Normal - No antibody detected.

1:20-1:80 = Weak Positive - Suggest repeat testing in 2-3 weeks with fresh specimen.

1:160 or greater = Positive - Suggestive of autoimmune hepatitis or chronic active hepatitis.

Note: In viral hepatitis, smooth muscle antibody titers are generally less than 1:80 and are transient. The titers in primary biliary cirrhosis are also low, ranging from 1:20 to 1:40.

No Appointment Necessary
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12 Patient Service Centers in Central New York.

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