Sirolimus SIR

Method(s) Liquid Chromatography-Tandem Mass Spectrometry
Synonym Rapamune®, Rapamycin®
Specimen Required
Collect One 3 mL lavender (EDTA) top tube. Specimen should be drawn 12 hours post-dose or prior to next dose (trough sample).
Transport 3 mL whole blood at 2-8°C. (Min: 1 mL)
Stability

Ambient 24 hours; Refrigerated: 1 week; Frozen: 2 months

Unacceptable Conditions

Clotted specimens

Schedule Daily
Billing Code 5010062
CPTCode 80195
Notes

Serial specimen collections should be consistent with respect to the last medication dose, as well as to the time of day, to minimize intra-individual variability.

Preferred Specimen Collection Device(s)
Reference Interval
 
 Therapeutic Range
Kidney transplant (in combination with Cyclosporine)4-12 ng/mL
Toxic valueGreater than 25 ng/mL
No Appointment Necessary
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12 Patient Service Centers in Central New York.

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