Metanephrines, Urine METU

Method(s) Quantitative High Performance Liquid Chromatography/ Tandem Mass Spectrometry
Specimen Required
Collect 24-hour urine or random urine. Refrigerate during collection.
Transport

Critical Frozen.

Remarks

Thoroughly mix entire collection in one container. Freeze specimen immediately after aliquoting. Do not exceed 4 mL in tubes.

Preserved: Transfer 4 mL to ARUP Transport tube with 20 mg Sulfamic Acid. Mix well (Min: 2.5 mL).

Alternative: If ARUP tube with Sulfamic Acid is not available, transfer 4 mL to ARUP transport tube and adjust pH to 2.0-4.0 with 6M HCI (Min: 2.5 mL).

Stability

Ambient: Unacceptable; Refrigerated: 2 weeks (unpreserved); Frozen 1 month (preserved)

Schedule Daily
Billing Code 5011190
CPTCode 83835
Preferred Specimen Collection Device(s)
Reference Interval

24 Hour calculations (24-hour Urine)

AgeMetanephrine
0-17 years
18 years and older
Not Established
152-1775 nmol
 Normetanephrine
0-17 years
18 years and older
Not Established
273-3548 nmol/d

Creatinine 24-Hour Urine

AgeMaleFemale
3-8 years
9-12 years
13-17 years
18-50 years
51-80 years
81 years and older
140-700 mg/d
300-1300 mg/d
500-2300 mg/d
1000-2500 mg/d
800-2100 mg/d
600-2000 mg/d
140-700 mg/d
300-1300 mg/d
400-1600 mg/d
700-1600 mg/d
500-1400 mg/d
400-1300 mg/d

Ratio to Creatinine (CRT) Calculations (Random Urine)

AgeMetanephrine
0-3 months
4-6 months
7-11 months
1 year
2-5 years
6-17 years
18 years and older
0-402 µmol/mol crt
0-373 µmol/mol crt
0-373 µmol/mol crt
0-304 µmol/mol crt
0-287 µmol/mol crt
0-184 µmol/mol crt
0-172 µmol/mol crt
 Normetanephrine
0-3 months
4-6 months
7-11 months
1 year
2-5 years
6-17 years
18 years and older
0-2098 µmol/mol crt
0-1357 µmol/mol crt
0-679 µmol/mol crt
0-802 µmol/mol crt
0-376 µmol/mol crt
0-278 µmol/mol crt
0-247 µmol/mol crt
No Appointment Necessary
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12 Patient Service Centers in Central New York.

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