Herpes Simplex Virus Type 1 and/or 2 Antibodies, IgG & IgM with Reflex to Type 1 & 2 Glycoprotein G-Specific Ab, IgG HSVGMR

Method(s) Enzyme Immunoassay, Multiplex Bead Immunoassay
Components

HSV 1/2 IgG
HSV 1/2 IgM

Specimen Required
Collect One 5 mL gold (SST) top tube.
Transport

1 mL serum at 2-8°C. (Min: 0.5 mL)

Stability

Ambient: 8 hours; Refrigerated: 7 days

Schedule Mon, Thur
Billing Code 2010211
CPTCode 86694 HSV IgG AND 86694 HSV IgM; If reflexed, add 86695 HSV type I, IgG and 86696 HSV type 2, IgG
Notes

Individuals infected with HSV may not exhibit detectable IgG antibody to glycoprotein G in the early stages of infection and 5-10% of infections may occur with glycoprotein G deficient virus. Detection of antibody presence in these cases may only be possible using a non-type specific screening test. HSV serology cannot be interpreted in infants less than 60 days old. Glycoprotein typing is not available for IgM.

Preferred Specimen Collection Device(s)
Reference Interval
ComponentReference Interval
Herpes Simplex Virus Type 1 and/or 2 Antibodies, IgGLess than 0.80: Negative

 0.80 - 0.99: Equivocal-Repeat in 10-14 days may be helpful.
 Greater than 0.99: Positive - May indicate a current or previous HSV infection.
Herpes Simplex Virus Type 1 and/or 2 Antibodies, IgMLess than 0.90: Negative

 0.90 - 1.09 IV: Equivocal - Repeat testing in 10-14 days may be helpful.
 Greater than 1.09: Positive - May indicate a current or recent infection.
Herpes Simplex Virus Type 1 Glycoprotein
G-Specific Antibody, IgG
Negative
Herpes Simplex Virus Type 2 Glycoprotein
G-Specific Antibody, IgG
Negative
No Appointment Necessary
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